She Has Her Mother’s Laugh audiobook cover - The Powers, Perversions, and Potential of Heredity

She Has Her Mother’s Laugh

The Powers, Perversions, and Potential of Heredity

Carl Zimmer

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She Has Her Mother’s Laugh
Cultural vs. Biological Inheritance+
Foundations of Genetics+
DNA and Genealogy+
Complex Traits+
Human Chimerism+
Cell Differentiation+
Epigenetics+
Genetic Mutations & Evolution+
Modern DNA Testing+

Quiz — Test Your Understanding

Question 1 of 8
Why did the Habsburg dynasty ultimately collapse according to modern genetic understanding?
  • A. They failed to adapt to the Roman system of hereditas, losing their wealth.
  • B. Their focus on maintaining blood purity through inbreeding led to severe genetic diseases and infertility.
  • C. They were exposed to an environmental pathogen that wiped out their specific gene pool.
  • D. A dominant allele for mental illness was introduced by a foreign monarch.
Question 2 of 8
What key genetic principle did Gregor Mendel discover through his experiments with pea plants?
  • A. Traits are determined by mitochondrial DNA inherited only from the mother.
  • B. Environmental factors play a larger role in plant height than inherited genetic factors.
  • C. Traits are encoded in alleles that can be either dominant or recessive.
  • D. First-generation hybrid plants always exhibit a blend of recessive traits.
Question 3 of 8
How did forensic scientist Peter Gill confirm the identities of the Romanov family remains found in 1991?
  • A. By analyzing the noncoding DNA responsible for lactase production.
  • B. By using Ludwig Herzfeld's blood-typing rules to match them with living Russian relatives.
  • C. By comparing their mitochondrial DNA to a living descendant of Queen Victoria.
  • D. By testing for specific genetic diseases prevalent in European royal families.
Question 4 of 8
What does the heritability of human height demonstrate about genetics?
  • A. Height is determined by a single dominant gene, making it 100% predictable.
  • B. Height is entirely dictated by environmental factors like childhood nutrition.
  • C. Height is determined by the interplay of multiple genes and can be influenced by environmental factors.
  • D. Short parents cannot genetically produce tall children due to recessive alleles.
Question 5 of 8
The cases of Mrs. McK and Lydia Fairchild illustrate which surprising genetic phenomenon?
  • A. Human chimerism, where a single person can possess two distinct sets of DNA.
  • B. Genetic methylation, where environmental trauma alters a person's DNA sequence.
  • C. Pluripotency, where adult cells revert to an embryonic state to heal injuries.
  • D. Spontaneous mutation, where a person's blood type changes over their lifetime.
Question 6 of 8
How does a single pluripotent zygote differentiate into the specialized cells of a complex human body?
  • A. It absorbs genetic material from the mother's mitochondrial DNA.
  • B. It uses a process called methylation to switch off specific genes, fixing the cell's function.
  • C. It continually creates new coding DNA as the embryo develops.
  • D. It relies entirely on the noncoding DNA to physically restructure the cell membrane.
Question 7 of 8
What did studies involving mice exposed to vinclozolin and acetophenone reveal about heredity?
  • A. Genetic mutations only occur when an organism is exposed to lethal amounts of radiation.
  • B. Learned behaviors and acquired traits from environmental stress can be passed down to subsequent generations.
  • C. Innate traits like eye color can be permanently altered by chemical exposure in utero.
  • D. Mice are uniquely immune to genetic changes caused by environmental trauma.
Question 8 of 8
Why are some humans able to digest milk products into adulthood while the majority cannot?
  • A. They have a mutation in their coding DNA that creates a completely new enzyme for digesting milk.
  • B. They inherited a dominant allele from a different mammalian species through early cross-breeding.
  • C. They gradually altered their digestive tracts through continuous consumption of dairy over their lifetimes.
  • D. They possess a mutation in their noncoding DNA that prevents the deactivation of the lactase-producing gene.

She Has Her Mother’s Laugh — Full Chapter Overview

She Has Her Mother’s Laugh Summary & Overview

She Has Her Mother’s Laugh (2018) probes the contemporary understanding of genetics and heredity, and provides an accessible history of the subject from the time of the Ancient Greeks onwards. Author Carl Zimmer also looks to the future, forecasting genetic developments on the horizon and unpacking what they might mean for humanity.

Who Should Listen to She Has Her Mother’s Laugh?

  • Science enthusiasts who want to round out their understanding of genetics and DNA
  • History buffs who enjoy reading about science and medicine
  • Amateur genealogists with an interest in getting to the roots of their family trees

About the Author: Carl Zimmer

Carl Zimmer is a science journalist who reports on genetics, evolution, and parasites in “Matter,” his New York Times column. He is also the author of many popular science books, which have won him accolades such as the Stephen Jay Gould Prize, the Science in Society Journalism Award, and a Guggenheim Fellowship.

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